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Tlr4 Deficiency Protects against Cardiac Pressure Overload Induced Hyperinflammation
Transverse aortic constriction provokes a pro-inflammatory reaction and results in cardiac hypertrophy. Endogenous ligands contribute to cardiac hypertrophy via toll-like receptor (TLR)-4 binding. A lack of TLR4 signaling diminishes hypertrophy and inflammation. Wild type mice undergoing aortic cons...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654478/ https://ncbi.nlm.nih.gov/pubmed/26588247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142921 |
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