Tlr4 Deficiency Protects against Cardiac Pressure Overload Induced Hyperinflammation

Transverse aortic constriction provokes a pro-inflammatory reaction and results in cardiac hypertrophy. Endogenous ligands contribute to cardiac hypertrophy via toll-like receptor (TLR)-4 binding. A lack of TLR4 signaling diminishes hypertrophy and inflammation. Wild type mice undergoing aortic cons...

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Publicat a:PLoS One
Autors principals: Ehrentraut, Heidi, Felix Ehrentraut, Stefan, Boehm, Olaf, El Aissati, Sakina, Foltz, Fabian, Goelz, Lina, Goertz, David, Kebir, Sied, Weisheit, Christina, Wolf, Michael, Meyer, Rainer, Baumgarten, Georg
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654478/
https://ncbi.nlm.nih.gov/pubmed/26588247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142921
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