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Tlr4 Deficiency Protects against Cardiac Pressure Overload Induced Hyperinflammation
Transverse aortic constriction provokes a pro-inflammatory reaction and results in cardiac hypertrophy. Endogenous ligands contribute to cardiac hypertrophy via toll-like receptor (TLR)-4 binding. A lack of TLR4 signaling diminishes hypertrophy and inflammation. Wild type mice undergoing aortic cons...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654478/ https://ncbi.nlm.nih.gov/pubmed/26588247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142921 |
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