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A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

The signals involved in axonal trafficking and presynaptic clustering are poorly defined. Here we show that targeting of the γ-aminobutyric acid–synthesizing enzyme glutamate decarboxylase 65 (GAD65) to presynaptic clusters is mediated by its palmitoylated 60-aa NH(2)-terminal domain and that this r...

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Bibliografski detalji
Glavni autori: Kanaani, Jamil, El-Husseini, Alaa El-Din, Aguilera-Moreno, Andrea, Diacovo, Julia M., Bredt, David S., Baekkeskov, Steinunn
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173248/
https://ncbi.nlm.nih.gov/pubmed/12356867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205053
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