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Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clusters
The inhibitory neurotransmitter γ-amino butyric acid (GABA) is synthesized by two isoforms of the enzyme glutamic acid decarboxylase (GAD): GAD65 and GAD67. Whereas GAD67 is constitutively active and produces >90% of GABA in the central nervous system, GAD65 is transiently activated and augments...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Rockefeller University Press
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935578/ https://ncbi.nlm.nih.gov/pubmed/20805323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912101 |
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