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A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
Signals transduced by kinases depend on the extent and duration of substrate phosphorylation. We generated genetically encoded fluorescent reporters for PKC activity that reversibly respond to stimuli activating PKC. Specifically, phosphorylation of the reporter expressed in mammalian cells causes c...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172956/ https://ncbi.nlm.nih.gov/pubmed/12782683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302125 |
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