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Genetically encoded fluorescent reporters to visualize protein kinase C activation in live cells

Protein kinase C (PKC) signaling drives many important cellular processes and its dysregulation results in pathophysiologies such as cancer(1). Because PKC is activated acutely and allosterically, it is difficult to monitor the cellular activity of endogenous PKC by conventional methodologies(2). Ra...

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Autors principals: Gallegos, Lisa L., Newton, Alexandra C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048020/
https://ncbi.nlm.nih.gov/pubmed/21870234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-160-4_17
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