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Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells

The complexity and specificity of many forms of signal transduction are widely believed to require spatial compartmentation of protein kinase and phosphatase activities, yet existing methods for measuring kinase activities in cells lack generality or spatial or temporal resolution. We present three...

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Detalhes bibliográficos
Main Authors: Ting, Alice Y., Kain, Kristin H., Klemke, Richard L., Tsien, Roger Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC64973/
https://ncbi.nlm.nih.gov/pubmed/11752449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211564598
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