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The primacy of affinity over clustering in regulation of adhesiveness of the integrin α(L)β(2)

Dynamic regulation of integrin adhesiveness is required for immune cell–cell interactions and leukocyte migration. Here, we investigate the relationship between cell adhesion and integrin microclustering as measured by fluorescence resonance energy transfer, and macroclustering as measured by high r...

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Autori principali: Kim, Minsoo, Carman, Christopher V., Yang, Wei, Salas, Azucena, Springer, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172602/
https://ncbi.nlm.nih.gov/pubmed/15611342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404160
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