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A Small Molecule Agonist of an Integrin,α(L)β(2)
The binding of integrin α(L)β(2) to its ligand intercellular adhesion molecule-1 is required for immune responses and leukocyte trafficking. Small molecule antagonists of α(L)β(2) are under intense investigation as potential anti-inflammatory drugs. We describe for the first time a small molecule in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764823/ https://ncbi.nlm.nih.gov/pubmed/17023419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M606888200 |
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