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Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin α(X)β(2)

The structural integrity of tissue proteins is damaged in processes ranging from remodeling of the extracellular matrix to destruction by microbial pathogens. Leukocytes play a prominent role in tissue surveillance and repair. However, it remains enigmatic what features of structurally decayed prote...

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Detalhes bibliográficos
Main Authors: Vorup-Jensen, Thomas, Carman, Christopher V., Shimaoka, Motomu, Schuck, Peter, Svitel, Juraj, Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547869/
https://ncbi.nlm.nih.gov/pubmed/15665082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409057102
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