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Structure and allosteric regulation of the αXβ2 integrin I domain
The integrin αXβ2 (CD11c/CD18, p150,95) binds ligands through the I domain of the αX subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of αXβ2 on dendritic cells and on other leukocytes, suggests a role in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149926/ https://ncbi.nlm.nih.gov/pubmed/12554829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0237387100 |
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