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Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
Stress-induced eukaryotic translation initiation factor 2 (eIF2) α phosphorylation paradoxically increases translation of the metazoan activating transcription factor 4 (ATF4), activating the integrated stress response (ISR), a pro-survival gene expression program. Previous studies implicated the 5′...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172506/ https://ncbi.nlm.nih.gov/pubmed/15479734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408003 |
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