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Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

Translation regulation largely occurs during initiation, which features ribosome assembly onto mRNAs and selection of the translation start site. Short, upstream ORFs (uORFs) located in the 5′-leader of the mRNA can be selected for translation. Multiple transcripts associated with stress amelioratio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Young, Sara K., Wek, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016099/
https://ncbi.nlm.nih.gov/pubmed/27358398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R116.733899
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