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Translation of upstream open reading frames in a model of neuronal differentiation

BACKGROUND: Upstream open reading frames (uORFs) initiate translation within mRNA 5′ leaders, and have the potential to alter main coding sequence (CDS) translation on transcripts in which they reside. Ribosome profiling (RP) studies suggest that translating ribosomes are pervasive within 5′ leaders...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Rodriguez, Caitlin M., Chun, Sang Y., Mills, Ryan E., Todd, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528255/
https://ncbi.nlm.nih.gov/pubmed/31109297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5775-1
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