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Translational Regulation of Human Methionine Synthase by Upstream Open Reading Frames

Methionine synthase is a key enzyme poised at the intersection of folate and sulfur metabolism and functions to reclaim homocysteine to the methionine cycle. The 5′ leader sequence in human MS is 394 nucleotides long and harbors two open reading frames (uORFs). In this study, regulation of the main...

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Autors principals: Col, Bekir, Oltean, Sebastian, Banerjee, Ruma
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682437/
https://ncbi.nlm.nih.gov/pubmed/17683808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbaexp.2007.06.003
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