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Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

Translation regulation largely occurs during initiation, which features ribosome assembly onto mRNAs and selection of the translation start site. Short, upstream ORFs (uORFs) located in the 5′-leader of the mRNA can be selected for translation. Multiple transcripts associated with stress amelioratio...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Young, Sara K., Wek, Ronald C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016099/
https://ncbi.nlm.nih.gov/pubmed/27358398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R116.733899
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