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A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1

In the unfolded protein response, the type I transmembrane protein Ire1 transmits an endoplasmic reticulum (ER) stress signal to the cytoplasm. We previously reported that under nonstressed conditions, the ER chaperone BiP binds and represses Ire1. It is still unclear how this event contributes to t...

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Hlavní autoři: Kimata, Yukio, Oikawa, Daisuke, Shimizu, Yusuke, Ishiwata-Kimata, Yuki, Kohno, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172501/
https://ncbi.nlm.nih.gov/pubmed/15520230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405153
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