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A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1

In the unfolded protein response, the type I transmembrane protein Ire1 transmits an endoplasmic reticulum (ER) stress signal to the cytoplasm. We previously reported that under nonstressed conditions, the ER chaperone BiP binds and represses Ire1. It is still unclear how this event contributes to t...

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Bibliografski detalji
Glavni autori: Kimata, Yukio, Oikawa, Daisuke, Shimizu, Yusuke, Ishiwata-Kimata, Yuki, Kohno, Kenji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172501/
https://ncbi.nlm.nih.gov/pubmed/15520230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405153
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