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A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
In the unfolded protein response, the type I transmembrane protein Ire1 transmits an endoplasmic reticulum (ER) stress signal to the cytoplasm. We previously reported that under nonstressed conditions, the ER chaperone BiP binds and represses Ire1. It is still unclear how this event contributes to t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172501/ https://ncbi.nlm.nih.gov/pubmed/15520230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405153 |
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