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Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells
Although compelling evidence supports the central role of caspase-activated DNase (CAD) in oligonucleosomal DNA fragmentation in apoptotic nuclei, the regulation of CAD activity remains elusive in vivo. We used fluorescence photobleaching and biochemical techniques to investigate the molecular dynam...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172457/ https://ncbi.nlm.nih.gov/pubmed/15569712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404105 |
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