Aberrant caspase-activated DNase (CAD) transcripts in human hepatoma cells

The gene of caspase-activated DNase (CAD), the key enzyme for nucleosome cleavage during apoptosis, is mapped at chromosome 1p36, a region usually associated with hemizygous deletions in human cancers, particularly in hepatoma (HCC). It is tempting to speculate that CAD plays a tumour-suppressive ro...

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Detalhes bibliográficos
Main Authors: Hsieh, S Y, Liaw, S F, Lee, S N, Hsieh, P S, Lin, K H, Chu, C M, Liaw, Y F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Molecular and Cellular Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377037/
https://ncbi.nlm.nih.gov/pubmed/12610505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600695
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