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Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells

Although compelling evidence supports the central role of caspase-activated DNase (CAD) in oligonucleosomal DNA fragmentation in apoptotic nuclei, the regulation of CAD activity remains elusive in vivo. We used fluorescence photobleaching and biochemical techniques to investigate the molecular dynam...

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Detalles Bibliográficos
Main Authors: Lechardeur, Delphine, Xu, Ming, Lukacs, Gergely L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172457/
https://ncbi.nlm.nih.gov/pubmed/15569712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404105
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