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Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells

Although compelling evidence supports the central role of caspase-activated DNase (CAD) in oligonucleosomal DNA fragmentation in apoptotic nuclei, the regulation of CAD activity remains elusive in vivo. We used fluorescence photobleaching and biochemical techniques to investigate the molecular dynam...

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Detalhes bibliográficos
Main Authors: Lechardeur, Delphine, Xu, Ming, Lukacs, Gergely L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172457/
https://ncbi.nlm.nih.gov/pubmed/15569712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404105
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