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Caspase-Activated DNase is Required to Maintain Tolerance to Lupus Nuclear AutoAntigens
OBJECTIVE: Caspase Activated DNase (CAD) is an endonuclease that is activated by active caspase 3 during apoptosis and is responsible for degradation of chromatin into nucleosomal units. These nucleosomal units are then included in apoptotic bodies. The presence of apoptotic bodies is considered imp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292632/ https://ncbi.nlm.nih.gov/pubmed/22127758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33448 |
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