Caspase-Activated DNase is Required to Maintain Tolerance to Lupus Nuclear AutoAntigens

OBJECTIVE: Caspase Activated DNase (CAD) is an endonuclease that is activated by active caspase 3 during apoptosis and is responsible for degradation of chromatin into nucleosomal units. These nucleosomal units are then included in apoptotic bodies. The presence of apoptotic bodies is considered imp...

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Detaylı Bibliyografya
Asıl Yazarlar: Jog, Neelakshi R., Frisoni, Lorenza, Shi, Qin, Monestier, Marc, Hernandez, Sairy, Craft, Joe, Luning Prak, Eline T., Caricchio, Roberto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292632/
https://ncbi.nlm.nih.gov/pubmed/22127758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33448
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