Caspase-Activated DNase is Required to Maintain Tolerance to Lupus Nuclear AutoAntigens

OBJECTIVE: Caspase Activated DNase (CAD) is an endonuclease that is activated by active caspase 3 during apoptosis and is responsible for degradation of chromatin into nucleosomal units. These nucleosomal units are then included in apoptotic bodies. The presence of apoptotic bodies is considered imp...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Jog, Neelakshi R., Frisoni, Lorenza, Shi, Qin, Monestier, Marc, Hernandez, Sairy, Craft, Joe, Luning Prak, Eline T., Caricchio, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292632/
https://ncbi.nlm.nih.gov/pubmed/22127758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33448
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk