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GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor

The cascade of phosphorylation is a pivotal event in transforming growth factor β (TGFβ) signaling. Reversible phosphorylation regulates fundamental aspects of cell activity. TGFβ-induced Smad7 binds to type I receptor (TGFβ type I receptor; TβRI) functioning as a receptor kinase antagonist. We foun...

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Detalhes bibliográficos
Main Authors: Shi, Weibin, Sun, Chuanxi, He, Bin, Xiong, Wencheng, Shi, Xingming, Yao, Dachun, Cao, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172339/
https://ncbi.nlm.nih.gov/pubmed/14718519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307151
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