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GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor
The cascade of phosphorylation is a pivotal event in transforming growth factor β (TGFβ) signaling. Reversible phosphorylation regulates fundamental aspects of cell activity. TGFβ-induced Smad7 binds to type I receptor (TGFβ type I receptor; TβRI) functioning as a receptor kinase antagonist. We foun...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172339/ https://ncbi.nlm.nih.gov/pubmed/14718519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307151 |
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