The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins

Insulin-like growth factors elicit many responses through activation of phosphoinositide 3-OH kinase (PI3K). The tuberous sclerosis complex (TSC1-2) suppresses cell growth by negatively regulating a protein kinase, p70S6K (S6K1), which generally requires PI3K signals for its activation. Here, we sho...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Harrington, Laura S., Findlay, Greg M., Gray, Alex, Tolkacheva, Tatiana, Wigfield, Simon, Rebholz, Heike, Barnett, Jill, Leslie, Nick R., Cheng, Susan, Shepherd, Peter R., Gout, Ivan, Downes, C. Peter, Lamb, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172316/
https://ncbi.nlm.nih.gov/pubmed/15249583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403069
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados