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Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway
Amyloid-β peptide (Aβ) accumulation in senile plaques, a pathological hallmark of Alzheimer's disease (AD), has been implicated in neuronal degeneration. We have recently demonstrated that Aβ induced oligodendrocyte (OLG) apoptosis, suggesting a role in white matter pathology in AD. Here, we ex...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171973/ https://ncbi.nlm.nih.gov/pubmed/14709545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307017 |
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