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The subendothelial extracellular matrix modulates NF-κB activation by flow: a potential role in atherosclerosis
Atherosclerotic plaque forms in regions of the vasculature exposed to disturbed flow. NF-κB activation by fluid flow, leading to expression of target genes such as E-selectin, ICAM-1, and VCAM-1, may regulate early monocyte recruitment and fatty streak formation. Flow-induced NF-κB activation is dow...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171897/ https://ncbi.nlm.nih.gov/pubmed/15809308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200410073 |
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