Broad and Gag-Biased HIV-1 Epitope Repertoires Are Associated with Lower Viral Loads

BACKGROUND: HLA class-I alleles differ in their ability to control HIV replication through cell-mediated immune responses. No consistent associations have been found between the breadth of Cytotoxic T Lymphocytes (CTL) responses and the control of HIV-1, and it is unknown whether the size or distrib...

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Detalhes bibliográficos
Main Authors: Rolland, Morgane, Heckerman, David, Deng, Wenjie, Rousseau, Christine M., Coovadia, Hoosen, Bishop, Karen, Goulder, Philip J. R., Walker, Bruce D., Brander, Christian, Mullins, James I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170517/
https://ncbi.nlm.nih.gov/pubmed/18183304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001424
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