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DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity
The ATM protein kinase is essential for cells to repair and survive genotoxic events. The activation of ATM's kinase activity involves acetylation of ATM by the Tip60 histone acetyltransferase. In this study, systematic mutagenesis of lysine residues was used to identify regulatory ATM acetylat...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169409/ https://ncbi.nlm.nih.gov/pubmed/17923702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01382-07 |
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