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Antiviral Antibodies Are Necessary To Prevent Cytotoxic T-Lymphocyte Escape in Mice Infected with a Coronavirus

Mutation within virus-derived CD8 T-cell epitopes can effectively abrogate cytotoxic T-lymphocyte (CTL) recognition and impede virus clearance in infected hosts. These so-called “CTL escape variant viruses” are commonly selected during persistent infections and are associated with rapid disease prog...

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Autori principali: Butler, Noah S., Dandekar, Ajai A., Perlman, Stanley
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168833/
https://ncbi.nlm.nih.gov/pubmed/17913802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01580-07
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