Additive Effect of Neutralizing Antibody and Antiviral Drug Treatment in Preventing Virus Escape and Persistence

Poorly cytopathic or noncytopathic viruses can escape immune surveillance and establish a chronic infection. Here we exploited the strategy of combining antiviral drug treatment with the induction of a neutralizing antibody response to avoid the appearance of neutralization-resistant virus variants....

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Bibliographic Details
Main Authors: Seiler, Peter, Senn, Beatrice M., Klenerman, Paul, Kalinke, Ulrich, Hengartner, Hans, Zinkernagel, Rolf M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112085/
https://ncbi.nlm.nih.gov/pubmed/10846070
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