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Additive Effect of Neutralizing Antibody and Antiviral Drug Treatment in Preventing Virus Escape and Persistence

Poorly cytopathic or noncytopathic viruses can escape immune surveillance and establish a chronic infection. Here we exploited the strategy of combining antiviral drug treatment with the induction of a neutralizing antibody response to avoid the appearance of neutralization-resistant virus variants....

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Seiler, Peter, Senn, Beatrice M., Klenerman, Paul, Kalinke, Ulrich, Hengartner, Hans, Zinkernagel, Rolf M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.5896-5901.2000
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