Additive Effect of Neutralizing Antibody and Antiviral Drug Treatment in Preventing Virus Escape and Persistence

Poorly cytopathic or noncytopathic viruses can escape immune surveillance and establish a chronic infection. Here we exploited the strategy of combining antiviral drug treatment with the induction of a neutralizing antibody response to avoid the appearance of neutralization-resistant virus variants....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Seiler, Peter, Senn, Beatrice M., Klenerman, Paul, Kalinke, Ulrich, Hengartner, Hans, Zinkernagel, Rolf M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.5896-5901.2000
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