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Antibody-Mediated Protection against Cytotoxic T-Cell Escape in Coronavirus-Induced Demyelination

C57BL/6 (B6) mice infected with mouse hepatitis virus (MHV) strain JHM develop a clinically evident, demyelinating encephalomyelitis. Infectious virus can be isolated from the spinal cords of these mice and is invariably mutated in the immunodominant CD8 T-cell epitope recognized in this strain. We...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Dandekar, Ajai A., Jacobsen, Gary, Waldschmidt, Thomas J., Perlman, Stanley
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14581523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.22.11867-11874.2003
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