CD4 T-Cell-Mediated Demyelination Is Increased in the Absence of Gamma Interferon in Mice Infected with Mouse Hepatitis Virus

Mice infected with the murine coronavirus, mouse hepatitis virus, strain JHM (MHV) develop an immune-mediated demyelinating encephalomyelitis. Adoptive transfer of MHV-immune splenocytes depleted of either CD4 or CD8 T cells to infected mice deficient in recombination activation gene 1 resulted in d...

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Pubblicato in:	J Virol
Autori principali:	Pewe, Lecia, Haring, Jodie, Perlman, Stanley
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7329-7333.2002
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