CD4 T-Cell-Mediated Demyelination Is Increased in the Absence of Gamma Interferon in Mice Infected with Mouse Hepatitis Virus

Mice infected with the murine coronavirus, mouse hepatitis virus, strain JHM (MHV) develop an immune-mediated demyelinating encephalomyelitis. Adoptive transfer of MHV-immune splenocytes depleted of either CD4 or CD8 T cells to infected mice deficient in recombination activation gene 1 resulted in d...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Pewe, Lecia, Haring, Jodie, Perlman, Stanley
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2002
Onderwerpen:	Pathogenesis and Immunity
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7329-7333.2002
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