CD4 T-Cell-Mediated Demyelination Is Increased in the Absence of Gamma Interferon in Mice Infected with Mouse Hepatitis Virus

Mice infected with the murine coronavirus, mouse hepatitis virus, strain JHM (MHV) develop an immune-mediated demyelinating encephalomyelitis. Adoptive transfer of MHV-immune splenocytes depleted of either CD4 or CD8 T cells to infected mice deficient in recombination activation gene 1 resulted in d...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Pewe, Lecia, Haring, Jodie, Perlman, Stanley
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7329-7333.2002
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