CD4 T-Cell-Mediated Demyelination Is Increased in the Absence of Gamma Interferon in Mice Infected with Mouse Hepatitis Virus

Mice infected with the murine coronavirus, mouse hepatitis virus, strain JHM (MHV) develop an immune-mediated demyelinating encephalomyelitis. Adoptive transfer of MHV-immune splenocytes depleted of either CD4 or CD8 T cells to infected mice deficient in recombination activation gene 1 resulted in d...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Pewe, Lecia, Haring, Jodie, Perlman, Stanley
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Pathogenesis and Immunity
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7329-7333.2002
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