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Important Roles for Gamma Interferon and NKG2D in γδ T-Cell-Induced Demyelination in T-Cell Receptor β-Deficient Mice Infected with a Coronavirus

γδ T cells mediate demyelination in athymic (nude) mice infected with the neurotropic coronavirus mouse hepatitis virus strain JHM. Now, we show that these cells also mediate the same process in mice lacking αβ T cells (T-cell receptor β-deficient [TCRβ(−/−)] mice) and demyelination is gamma interfe...

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Detalhes bibliográficos
Main Authors: Dandekar, Ajai A., O'Malley, Katherine, Perlman, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181615/
https://ncbi.nlm.nih.gov/pubmed/16014902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9388-9396.2005
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