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Bystander CD8 T-Cell-Mediated Demyelination is Interferon-γ-Dependent in a Coronavirus Model of Multiple Sclerosis

Mice infected with the coronavirus mouse hepatitis virus, strain JHM (JHM) develop a disease that shares many histological characteristics with multiple sclerosis. We previously demonstrated that JHM-infected mice that only have CD8 T cells specific for an epitope not in the virus develop demyelinat...

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Autori principali: Dandekar, Ajai A., Anghelina, Daniela, Perlman, Stanley
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602263/
https://ncbi.nlm.nih.gov/pubmed/14742242
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