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Pol-Specific CD8(+) T Cells Recognize Simian Immunodeficiency Virus-Infected Cells Prior to Nef-Mediated Major Histocompatibility Complex Class I Downregulation
Effective, vaccine-induced CD8(+) T-cell responses should recognize infected cells early enough to prevent production of progeny virions. We have recently shown that Gag-specific CD8(+) T cells recognize simian immunodeficiency virus-infected cells at 2 h postinfection, whereas Env-specific CD8(+) T...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2168778/ https://ncbi.nlm.nih.gov/pubmed/17699580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00926-07 |
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