Simian Immunodeficiency Virus-Specific CD8(+) T Cells Recognize Vpr- and Rev-Derived Epitopes Early after Infection

The kinetics of CD8(+) T cell epitope presentation contribute to the antiviral efficacy of these cells yet remain poorly defined. Here, we demonstrate presentation of virion-derived Vpr peptide epitopes early after viral penetration and prior to presentation of Vif-derived epitopes, which required d...

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Autores principales: Sacha, Jonah B., Buechler, Matthew B., Newman, Laura P., Reed, Jason, Wallace, Lyle T., Loffredo, John T., Wilson, Nancy A., Watkins, David I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950557/
https://ncbi.nlm.nih.gov/pubmed/20686015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01357-10
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