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The Aspergillus fumigatus Transcriptional Regulator AfYap1 Represents the Major Regulator for Defense against Reactive Oxygen Intermediates but Is Dispensable for Pathogenicity in an Intranasal Mouse Infection Model

Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly suggested. Therefore, we investigated the enzymatic ROI detoxifying system by proteome analysis of A. fumigatus challen...

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Bibliografski detalji
Glavni autori: Lessing, Franziska, Kniemeyer, Olaf, Wozniok, Iwona, Loeffler, Juergen, Kurzai, Oliver, Haertl, Albert, Brakhage, Axel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168236/
https://ncbi.nlm.nih.gov/pubmed/17921349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00267-07
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