Impact of Mycophenolic Acid on the Functionality of Human Polymorphonuclear Neutrophils and Dendritic Cells during Interaction with Aspergillus fumigatus

Mycophenolic acid (MPA) is used clinically to prevent graft rejection but may increase the risk of fungal infection. We observed that MPA enhanced the Aspergillus fumigatus-induced oxidative burst of polymorphonuclear neutrophils, but without a corresponding increase in fungal killing. Furthermore,...

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Detalhes bibliográficos
Main Authors: Mezger, Markus, Wozniok, Iwona, Blockhaus, Christian, Kurzai, Oliver, Hebart, Holger, Einsele, Hermann, Loeffler, Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Biologic Response Modifiers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443887/
https://ncbi.nlm.nih.gov/pubmed/18426895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01618-07
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