Impact of Mycophenolic Acid on the Functionality of Human Polymorphonuclear Neutrophils and Dendritic Cells during Interaction with Aspergillus fumigatus

Mycophenolic acid (MPA) is used clinically to prevent graft rejection but may increase the risk of fungal infection. We observed that MPA enhanced the Aspergillus fumigatus-induced oxidative burst of polymorphonuclear neutrophils, but without a corresponding increase in fungal killing. Furthermore,...

Full description

Saved in:
Bibliographic Details
Main Authors: Mezger, Markus, Wozniok, Iwona, Blockhaus, Christian, Kurzai, Oliver, Hebart, Holger, Einsele, Hermann, Loeffler, Juergen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Biologic Response Modifiers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443887/
https://ncbi.nlm.nih.gov/pubmed/18426895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01618-07
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items