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The Aspergillus fumigatus Transcriptional Regulator AfYap1 Represents the Major Regulator for Defense against Reactive Oxygen Intermediates but Is Dispensable for Pathogenicity in an Intranasal Mouse Infection Model

Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly suggested. Therefore, we investigated the enzymatic ROI detoxifying system by proteome analysis of A. fumigatus challen...

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Bibliografische gegevens
Hoofdauteurs: Lessing, Franziska, Kniemeyer, Olaf, Wozniok, Iwona, Loeffler, Juergen, Kurzai, Oliver, Haertl, Albert, Brakhage, Axel A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168236/
https://ncbi.nlm.nih.gov/pubmed/17921349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00267-07
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