The Aspergillus fumigatus Transcriptional Regulator AfYap1 Represents the Major Regulator for Defense against Reactive Oxygen Intermediates but Is Dispensable for Pathogenicity in an Intranasal Mouse Infection Model

Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly suggested. Therefore, we investigated the enzymatic ROI detoxifying system by proteome analysis of A. fumigatus challen...

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Main Authors: Lessing, Franziska, Kniemeyer, Olaf, Wozniok, Iwona, Loeffler, Juergen, Kurzai, Oliver, Haertl, Albert, Brakhage, Axel A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168236/
https://ncbi.nlm.nih.gov/pubmed/17921349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00267-07
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