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The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons
Local anesthetics (LAs) block the generation and propagation of action potentials by interacting with specific sites of voltage-gated Na(+) channels. LAs can also excite sensory neurons and be neurotoxic through mechanisms that are as yet undefined. Nonspecific cation channels of the transient recep...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2157564/ https://ncbi.nlm.nih.gov/pubmed/18172555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32751 |
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