The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons

Local anesthetics (LAs) block the generation and propagation of action potentials by interacting with specific sites of voltage-gated Na(+) channels. LAs can also excite sensory neurons and be neurotoxic through mechanisms that are as yet undefined. Nonspecific cation channels of the transient recep...

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Detaylı Bibliyografya
Asıl Yazarlar: Leffler, Andreas, Fischer, Michael J., Rehner, Dietlinde, Kienel, Stephanie, Kistner, Katrin, Sauer, Susanne K., Gavva, Narender R., Reeh, Peter W., Nau, Carla
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2157564/
https://ncbi.nlm.nih.gov/pubmed/18172555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32751
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