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Transgenic Gαq overexpression induces cardiac contractile failure in mice

The critical cell signals that trigger cardiac hypertrophy and regulate the transition to heart failure are not known. To determine the role of Gαq-mediated signaling pathways in these events, transgenic mice were constructed that overexpressed wild-type Gαq in the heart using the α-myosin heavy cha...

詳細記述

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書誌詳細
主要な著者: D’Angelo, Drew D., Sakata, Yoshihito, Lorenz, John N., Boivin, Gregory P., Walsh, Richard A., Liggett, Stephen B., Dorn, Gerald W.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC21567/
https://ncbi.nlm.nih.gov/pubmed/9223325
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